This happens due to abnormal levels of histamine, but the mechanism that causes the increase in the levels of histamine is unclear. Dandy-Walker Malformation can cause swelling of the brain. The disease is characterized by a high fever, sore throat, headache, weakness, tremors, and falling asleep anywhere. These are medical conditions that are so strange, you might not have even heard of them yet. 10. Rabson-Mendenhall syndrome is inherited as an autosomal recessive trait. Bright Side has found 12 very rare conditions. Not much has changed since then. We use cookies to personalise content and ads, to provide social media features and to analyse our traffic. The worst thing is that the person may not sense the smell, but other people do. The most well-known person with this disease was an American man named Paul Karason who had the nickname "Papa Smurf" because he looked very similar to the cartoon character.
This causes a lot of psychological problems and communication difficulties. This rare genetic disorder causes multiple strokes. 15: Leukocyte Adhesions Deficiency (LAD) Syndromes.

But now we're also terrified. Symptoms of this disease include skin rashes.

Their causes are still unexplored even in the 21st century. Poor health is one of those things, like divorce and the loss of a loved one, that you know will touch your life at some point but would rather not think about too much. And this disease is actually not that rare. LAD syndromes are characterized by dysfunctional white blood cells, which leads to higher rates of infection. Also known as "sleeping sickness," but idifferent from the sleeping sickness that the tsetse fly transmits.

It was carried from the Americas to Europe by the returning crewmen from Christopher Columbus's voyage. Imagine that you go to bed, and when you wake up, you realize that you have a completely different voice. This disease disrupts the synthesis of collagen which leads to: the fragility of blood vessels, over-flexibility of the joints, dislocations, sprains, tissue deformation and other dangerous consequences. Which of the diseases described in this article surprised you the most? As a result, a person's skin has a silverish or bluish color. First up: It feels awful to do it, and this disease makes you do it again and again and again…, 6 Of The Most Interesting Diseases To Have Ravaged Humanity. Other names for the disease include flesh-eating bacteria, which can infect the body through flesh wounds. Europeans brought many diseases to the Americas. This genetic disease is also known as the vampire syndrome because a person, who has it, can't be in the sunlight without severe consequences. There is no actual treatment, so a sick person may either recover themselves, or the sickness may become chronic and last for decades. Hypertrichosis is an overgrowth of hair in places where it's not considered normal, for example, on the face.

Hailey-Hailey syndrome is characterized by blisters and lesions. The skin of those who have this disease is elastic and very susceptible to damage and scarring.

Erdheim-Chester Disease affects multiple systems in the body.

The sheer range of diseases that affect humans is overwhelming, but it’s as infinitely interesting as it is exhausting. The only thing that can make them experience something that can remotely be described as fear, is the inhalation of a high dose of carbon dioxide which would make any healthy person panic. Parry Romberg Syndrome causes skin and soft tissues on half of the face to shrink. Symptoms of Wolman Disease include an enlarged spleen. Innate hypertrichosis can't be treated, but fortunately, nowadays there are a lot of ways to get rid of extra hair. In the medical world however, a disease is an abnormality that will impair bodily functions and is often associated with certain signs and symptoms. Certain especially interesting diseases, however, compel our attention and call into question the notion that humans have this whole “modern medicine” thing figured out. The person who has this syndrome can still speak their mother language, but their pronunciation changes so much that other people think that the person speaks with a foreign accent. If a person who has xeroderma needs to go outside in the daytime, they need to take all possible precautions. Selected as the most interesting among diseases related questions in Diseases quiz. You consent to our cookies if you continue to use our website. And this inflammation can lead to an oncology disease. This genetic disease is characterized by early onset of cataracts associated with persistently elevated levels of a protein known as ferritin in the blood plasma. For example, the boy David Middleton, who you can see on the photo, had to wear a special suit to school and spend two hours every day to out the protective cream. The mutation associated with this disease is inherited as an autosomal dominant trait, and cataracts are the only known complication associated with this rare disease. Right now, the clinical trial of a drug to treat this disease is being conducted. There are several variations of this syndrome — from moderate to severe (fortunately, the latter is very rare)and in cases where the disease doesn't affect the blood vessels, it doesn't really influence life expectancy. The development of argyria happens in situations when people use a lot of products which contain silver, and it is especially common among people who work with this metal. Doctors believe it to be viral, but the exact virus has yet to be determined. Menkes Disease is a disorder of copper metabolism. If you suffer often from insomnia and stress, there is a risk that you could experience this yourself. Eyes are in danger, too. This disease was first identified in the late 1800s among an isolated group of French Canadian lumberjacks. Syphilis was present in the Americas before European contact. This disease is also known as fish odor syndrome, and as you probably guessed, it leads to a person smelling like fish. This is how people who suffer from exploding head syndrome describe their symptoms. The spots on the skin which were exposed to ultraviolet, become inflammatory. With symptoms like rock eating, change in accent, and a lopsided face, here are six of history’s most interesting diseases. There are thousands of people who are deeply affected by rare diseases. This leads to "the explosion" and the sensation that feels like an electric shock. It's very odd, that tourists from Asia usually don't have Stendhal syndrome, perhaps because their culture is very different. Nematodes: Do We Still Need to Worry About Roundworms and Bare Feet? There is no treatment at the moment, but if a patient gets the right physiotherapy, it's possible to decrease the negative effects of Ehlers–Danlos syndrome.

The drug is supposed to stop the ossification process. 12 Deadly Diseases Cured in the 20th Century, Information about the device's operating system, Information about other identifiers assigned to the device, The IP address from which the device accesses a client's website or mobile application, Information about the user's activity on that device, including web pages and mobile apps visited or used, Information about the geographic location of the device when it accesses a website or mobile application. Seizures and mental retardation are signs of Mowat-Wilson Syndrome. The spots on the skin which were exposed to ultraviolet, become inflammatory. The thing that the writer experienced is a psychological disorder which presents with symptoms like rapid heartbeat, dizziness, fainting, confusion and even hallucinations when people experience something that is of great personal significance like art, the beauty of nature, animals, or people. Certain especially interesting diseases, however, compel our attention and call into question the notion that humans have this whole “modern medicine” thing figured out. When we hear about an outbreak of a flesh-eating bacteria or some other rare sickness, we're fascinated. Which disease did they carry back? Some interesting diseases count as such because their symptoms are so bizarre, others because they’re so incredibly rare, and still others because they’re so mysterious that doctors who study them have no choice but to shrug and guess that the sufferers are under a sorcerer’s curse. A symptomatic treatment (the only treatment there is): doctors recommend patients not to get cold, take anti-histamine medications, and put special creams on the face and hands before going outside for protection from cold. This rare and serious genetic illness is characterized by the gradual ossification of muscles, tendons, and ligaments. Whether they’re physical, mental, or both, these weird diseases are some of the most intriguing:. that showed that people affected with this condition are not afraid of snakes, poisonous spiders, horror movies, armed robberies, and other dangers. The epidemic was first discovered in 1915–1917. At least, we generally expect that somebody, somewhere is “working” on the problem. Pontocerebellar Hypoplasia is characterized by prenatal development of an abnormally small cerebellum and brain stem. He turned blue after he had been taking colloidal silver for a long time trying to treat his dermatitis. Weird & Wacky, Copyright © 2020 HowStuffWorks, a division of InfoSpace Holdings, LLC, a System1 Company. Although, the creepy bearded women from the circuses of the past could have been affected with this disorder.

There were experiments done on a patient known as S.M.

The same goes for the tourists from Italy, because they are more accustomed to being surrounded by beauty than other people. Pseudomyxoma Peritonei causes stomach pain and enlarged abdomen. But I’m Not.” Women Share What Life Is Like After a Divorce, 4 Perfect Spots to Spritz With Perfume and 4 Spots That Are No-Nos, A French Photographer Fell in Love With Vietnam and Called It a Mosaic of Contrasts. The patients who have this condition don't have the amygdala in their brains which means that they are unable to experience fear. "There is a noise that becomes louder and louder, then there is a sound of an explosion, and a bright flash of light, like someone turned on a flashlight and pointed it at my face." And this inflammation can lead to an oncology disease.

People Share Little-Known Facts That One Day Can Save Your Life, 19 Photos That Show Even Ordinary Things Can Reach Unimaginable Sizes, 4 Reasons You Need to Clean a Can Lid Before Opening It, A Guy Photoshops Our Favorite Animated Characters Into His Photos, and It’s Like a Childhood Dream Come True, Science Explains Why Your Phone Speaks Like a Woman, This Mom Faces Disapproval Because Her Son Wears a Leash and Backpack, and She Explains Her Reasoning, 20 Lucky People Who Bumped Into a Miracle When They Least Expected It, “I Thought I Would Be Sad Forever. Most of the time, hypertrichosis is found in men, and rarely in women. Lesch-Nyhan syndrome in and of itself isn’t particularly remarkable, but the behaviors that it causes in those who are afflicted make it a very interesting disease. At the moment, there are no effective preventive or treatment measures, but scientists managed to find the gene that is responsible for fibrodysplasia.
Lesch-Nyhan syndrome is a hereditary disorder with no known cure that’s characterized by a build-up of uric acid in all bodily fluids. The disorder itself is not dangerous to the person's health, but people say that they feel alien in their motherlands, and their lives become harder because of the misunderstanding and sometimes mockery from other people. Hyperferritinemia-Cataract Syndrome causes cataracts. The (Seriously Sweet) History of Doughnuts, 21 Fantastic Pictures Of Female Skateboarders From The 1970s, What Stephen Hawking Thinks Threatens Humankind The Most, 27 Raw Images Of When Punk Ruled New York, Join The All That's Interesting Weekly Dispatch. Scientists think that this syndrome may be caused by neural activity in the parts of the brain responsible for sound. This genetic disease is also known as the vampire syndrome because a person, who has it, can't be in the sunlight without severe consequences.

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